| 名稱 | CSF3R Q741*/BaF3 |
| 型號 | CBP73254 |
| 報價 |  |
| 特點 | CSF3R Q741*/BaF3,母細胞：BaF3，CSF3R，集落刺激因子 3 受體，編碼調節骨髓祖細胞增殖和分化的細胞因子受體（PMID：27789332）。 CSF3R 突變常見于慢性中性粒細胞白血病和急性髓系白血病（PMID：23896413，PMID：30348809）。 |
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藥靶細胞株 > kinase激酶細胞株 > CBP73254CSF3R Q741*/BaF3
- 詳細內容
CBP73254 | |
| I. Introduction | |
Cell Line Name： | CSF3R Q741*/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
CSF3R, colony stimulating factor 3 receptor, encodes a cytokine receptor regulating proliferation and differentiation of myeloid progenitor cells (PMID: 27789332). CSF3R mutations commonly occur in chronic neutrophilic leukemia and acute myeloid leukemia (PMID: 23896413, PMID: 30348809). | |
| III. Representative Data | |
1.WB of CSF3R Q741*/BaF3
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2. Anti-proliferation assay | |
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Figure 2. Anti-proliferation assay of three reference compounds on the CSF3R Q741*/BaF3. | |
