CBP74101 |
I. Background |
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. |
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II. Description |
Recombinant CHO cells constitutively expressing FCGR2B. |
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III. Introduction |
Host Cell: | CHO |
Expressed gene: | FCGR2B(FcγRIIb) |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12K+10%FBS+500ug/ml hygromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Functional(Report Gene) Assay |
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IV. Description of Host Cell Line |
Organism: | Mouse |
Tissue: | Ovary |
Disease: | Hamster Chinese ovary |
Morphology: | Epitheloid cell |
Growth Properties: | Adherent |
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Ⅴ. Representative Data |

Figure 1.Recombinant CHO cells constitutively expressing FCGR2B(FcγRIIb). |
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